{"id":4426,"date":"2025-04-03T01:30:00","date_gmt":"2025-04-03T01:30:00","guid":{"rendered":"https:\/\/weedman.ai\/?p=4426"},"modified":"2025-04-03T19:55:38","modified_gmt":"2025-04-03T19:55:38","slug":"un-estudio-a-largo-plazo-demuestra-que-el-cannabis-medicinal-mejora-el-bienestar-del-paciente-durante-todo-un-ano","status":"publish","type":"post","link":"https:\/\/weedman.ai\/es\/noticias\/medicina\/2025\/04\/03\/un-estudio-a-largo-plazo-demuestra-que-el-cannabis-medicinal-mejora-el-bienestar-del-paciente-durante-todo-un-ano\/","title":{"rendered":"Un estudio a largo plazo demuestra que el cannabis medicinal mejora el bienestar de los pacientes durante todo un a\u00f1o"},"content":{"rendered":"<p>Un reciente estudio a largo plazo ha descubierto que el cannabis medicinal mejora significativamente la calidad de vida de los pacientes que padecen enfermedades cr\u00f3nicas. La Iniciativa QUEST, llevada a cabo por investigadores de la Universidad de Sydney, realiz\u00f3 un seguimiento de los pacientes durante 12 meses para comprobar si los beneficios observados en los tres meses iniciales de consumo de aceite de cannabis pod\u00edan mantenerse. Los resultados, publicados en la revista PLOS One, indican que los que continuaron el tratamiento experimentaron mejoras continuas tanto en su salud f\u00edsica como mental.<\/p>\n\n\n\n<p>Muchas personas que padecen enfermedades cr\u00f3nicas se enfrentan a retos diarios, como dolor constante, trastornos del sue\u00f1o y estr\u00e9s emocional. Los tratamientos tradicionales suelen proporcionar un alivio limitado, y los efectos secundarios de la medicaci\u00f3n a largo plazo pueden mermar a\u00fan m\u00e1s la calidad de vida del paciente. El cannabis medicinal ha surgido como una alternativa potencial, ofreciendo una nueva esperanza a quienes no han respondido a las terapias convencionales.<\/p>\n\n\n\n<p>Desde que Australia legaliz\u00f3 el cannabis medicinal en 2016 para los pacientes que no responden a los tratamientos est\u00e1ndar, se ha recetado cannabis a m\u00e1s de un mill\u00f3n de personas para m\u00e1s de 200 afecciones de salud. La mayor\u00eda de los pacientes lo utilizan para controlar el dolor, los trastornos del sue\u00f1o, la ansiedad o la depresi\u00f3n. Los efectos terap\u00e9uticos del cannabis proceden de compuestos como el THC y el CBD, que ofrecen alternativas a los medicamentos opioides que conllevan riesgos como la adicci\u00f3n y el deterioro cognitivo.<\/p>\n\n\n\n<p>El estudio QUEST incluy\u00f3 a participantes de entre 18 y 97 a\u00f1os de 114 cl\u00ednicas entre noviembre de 2020 y diciembre de 2021. Los participantes completaron evaluaciones peri\u00f3dicas al inicio del estudio, a las dos semanas y en ocho momentos adicionales hasta los 12 meses. Informaron sobre su calidad de vida relacionada con la salud (CVRS), que abarca el bienestar f\u00edsico, emocional y cognitivo, as\u00ed como m\u00e9tricas como la fatiga, el dolor, el sue\u00f1o, la ansiedad y la depresi\u00f3n.<\/p>\n\n\n\n<p>Los resultados del estudio mostraron claras mejoras. Las puntuaciones de CVRS mejoraron r\u00e1pidamente y se mantuvieron altas durante todo el periodo de estudio. En concreto, las puntuaciones EQ-5D-5L aumentaron en 0,114 (d de Cohen = 0,52), y las puntuaciones QLQ-C30 aumentaron en 10,71 puntos (d = 0,91), lo que indica una mejora cl\u00ednica significativa. La intensidad y la interferencia del dolor disminuyeron notablemente, sobre todo entre los pacientes con dolor cr\u00f3nico, y la puntuaci\u00f3n PROMIS de interferencia del dolor mejor\u00f3 en 4,87 puntos (d = 0,76). Adem\u00e1s, los niveles de fatiga disminuyeron en 4,70 puntos (d = 0,51), y los trastornos del sue\u00f1o se redujeron en 5,96 puntos (d = 0,76).<\/p>\n\n\n\n<p>Los pacientes con ansiedad y depresi\u00f3n tambi\u00e9n experimentaron importantes beneficios del cannabis medicinal. Los que padec\u00edan trastornos depresivos experimentaron una reducci\u00f3n de las puntuaciones de depresi\u00f3n de 7,19 puntos (d = 0,65), lo que hizo que muchos participantes pasaran de s\u00edntomas graves a moderados. Del mismo modo, las puntuaciones de ansiedad mejoraron en 5,65 puntos (d = 0,69), superando el umbral cl\u00ednicamente reconocido de 5 puntos.<\/p>\n\n\n\n<p>El estudio tambi\u00e9n descubri\u00f3 que la proporci\u00f3n de THC y CBD en los aceites de cannabis influ\u00eda en los resultados. Los aceites en los que predominaba el THC se asociaron a una mayor mejor\u00eda de la ansiedad, la depresi\u00f3n, la fatiga y el sue\u00f1o, mientras que los aceites en los que predominaba el CBD eran m\u00e1s eficaces para tipos espec\u00edficos de dolor, como las cefaleas y el dolor relacionado con el c\u00e1ncer. El dolor musculoesquel\u00e9tico respondi\u00f3 mejor a los aceites con CBD dominante que a los que eran puramente CBD.<\/p>\n\n\n\n<p>Casi la mitad de los participantes declararon haber reducido el consumo de otros medicamentos con receta, y alrededor de 22% consum\u00edan opi\u00e1ceos cuando iniciaron el estudio. Al cabo de 12 meses, 70% de estos pacientes hab\u00edan reducido o abandonado por completo el consumo de opi\u00e1ceos. Sin embargo, las personas con trastornos del movimiento observaron mejoras en la CVRS, pero no mostraron cambios significativos en la funci\u00f3n de las extremidades superiores, con un aumento medio de la puntuaci\u00f3n de s\u00f3lo 1,43 puntos, lo que no alcanz\u00f3 el umbral cl\u00ednico de mejora.<\/p>\n\n\n\n<p>El estudio tambi\u00e9n observ\u00f3 que las tasas de finalizaci\u00f3n de los resultados comunicados por los pacientes disminuyeron con el tiempo, hasta situarse en 38% a los 12 meses. Los que abandonaron antes tendieron a mostrar menos mejor\u00eda, lo que sugiere que los participantes que continuaron con el tratamiento obtuvieron m\u00e1s beneficios del cannabis medicinal.<\/p>","protected":false},"excerpt":{"rendered":"<p>Un reciente estudio a largo plazo ha descubierto que el cannabis medicinal mejora significativamente la calidad de vida de los pacientes...<\/p>","protected":false},"author":2,"featured_media":4425,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[49,71],"tags":[93,215,1136],"class_list":["post-4426","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicine","category-research","tag-chronic-pain","tag-medicinal-cannabis","tag-university-of-sydney"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Long-term Study Shows Medicinal Cannabis Improves Patient Well-Being for a Full Year - 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